Seminars

Accelerate Targeted Protein Degradation Drug Discovery with Axcelead’s Integrated Platform, DegLead

Topic : Accelerate Targeted Protein Degradation Drug Discovery with Axcelead’s Integrated Platform, DegLead
Date : February 19, 2025, 3:00 PM PST | February 19, 2025, 6:00 PM EST | 30 Minutes
Location : Online Zoom Meeting

Webinar Overview :

Targeted Protein Degradation (TPD), including bifunctional degraders and molecular glue degraders, represents a paradigm shift in small molecule drug discovery. However, challenges remain in successfully discovering new TPD drugs. For example, bifunctional degraders face issues such as unfavorable ADME and physicochemical properties due to their molecular complexity. Regarding molecular glue degraders, the discovery of promising compounds often relies heavily on serendipity.

Axcelead, a pharma-originated integrated drug discovery solutions provider, established in 2017 as a spin-out from Takeda Pharmaceutical Company, has inherited drug discovery platforms from Takeda and Teijin Pharma. We have identified TPD as a key focus area and have developed proprietary integrated TPD solutions to address these challenges.

In this webinar, we will introduce our “DegLead Platform™,” an integrated TPD platform, and showcase how our strengths—including specialized chemistry, a comprehensive compound library, diverse assay systems, and advanced ADME solutions—can drive success in your TPD projects. Additionally, we will share application case studies and valuable insights.

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