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Irbesartan but not Roflumilast Ameliorates Renal Injury in a Col4a5 R471* Mutant Mouse Model of Alport Syndrome and CKD
Junko Yokoi2026-04-16T00:16:27+00:0004.16.2026|
  • Integrated Drug Discovery
  • Axcelead Booster
  • Target Identification / Validation
  • Hit Identification / Characterization
  • Lead Generation / Optimization
  • Candidate Selection
  • IND Enabling

Therapeutic Areas

  • Oncology
  • Immunology
  • Neuroscience
  • Cardiovascular / Metabolic Disease

Technology Platforms

  • High Throughput Screening
  • Chemistry
  • In Vitro/In Vivo Pharmacology
  • Omics
  • Bioinformatics
  • Genetically Modified Animal

Therapeutic Modalities

  • Small Molecules
    • – Small Molecules
    • – Targeted Protein Degraders (TPDs)
    • – RNA-Targeted Small Molecules
  • Oligonucleotide
  • Peptide

Resources

  • Videos
  • Presentations
  • Publications
  • Posters
  • Brochures

Events

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