Technology Platforms
Omics
Multiple Omics Platform for Precision Drug Discovery
Driving Translational Research and Innovation in Drug Discovery
Our advanced omics technologies provide a comprehensive view of biological systems, linking genes as blueprints, proteins as the building blocks of cells, and metabolites as indicators of phenotypic changes and cellular morphology. This approach helps overcome key challenges in drug discovery by:
- Uncovering hidden disease mechanisms
- Decoding mechanisms of action (MoA)
- Identifying dynamic biomarkers for better outcomes
- Stratifying patient subtypes for precision medicine
- Supporting hypothesis-driven and data-driven compound evaluation
Overcoming Challenges in Drug Discovery
Our omics platform is designed to solve the following critical obstacles in drug discovery by integrating high-resolution, cross-platform omics data, which accelerates drug discovery and development:
- Bridging gaps in disease pathophysiology
- Closing the gap between preclinical efficacy and human outcomes
- Identifying MoA for new compounds in complex disease models
- Early detection of off-target toxicological effects
- Finding relevant biomarkers for dynamic treatment monitoring
- Identifying patient subgroups with diverse responses
Our Key Capabilities
Project-tailored omics services categorized by platform with end-to-end support: study design, sample prep, data acquisition, bioinformatics and hypothesis generation.
- Somatic Mutation Custom Panel
- Single-cell RNA-seq
- Single-nucleus RNA-seq
- Spatial Transcriptomics
- Bulk RNA-seq
- Global Proteomics
- Post-Translational Modifications Proteomics
- Chemical Proteomics
- Proteogenomics
- Non-targeted metabolomics/lipidomics
- Wide-target metabolomics/lipidomics
- Focused Metabolite Panels
- Metabolic Flux Analysis
- Extracellular Vehicles Analysis
Bioinformatics & Data Integration
Integrate multiple omics layers (genomics, transcriptomics, proteomics, metabolomics) to meet specific research or clinical objectives, enabling a deeper understanding of biological systems and disease mechanisms
Why Choose Axcelead’s Omics Services
- Expert-designed, disease- and modality-specific workflows
- Development of quantification methods for biomarker validation and evaluation, supported by bioanalysis experts
- Proven performance across therapeutic areas including CNS, oncology, metabolic, and immune disorders
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- Support for human clinical and preclinical models
- Publication-ready reports featuring interactive data visualizations