Researcher Nagasaka from DMPK BU to Present a Poster at the 40th Annual Meeting of the Japanese Society for the Study of Xenobiotics

2025.10.09

Our researcher, Kosuke Nagasaka from the DMPK Business Unit, will present a poster at the 40th Annual Meeting of the Japanese Society for the Study of Xenobiotics, to be held from October 20 to 23, 2025, in Kyoto prefecture, Japan.
If you plan to attend the conference, we encourage you to join the session and hear the presentation.

Conference Name: the 40th Annual Meeting of the Japanese Society for the Study of Xenobiotics

Date & Time: October 23

Location: Kyoto International Exhibition Hall “Miyako Messe”

Title: Evaluation method for drug metabolism mediated by the human gut microbiota

Auther: Kosuke Nagasaka, Koichi Shiga and Kazunobu Aoyama

Presentation number: P-059

Presenter: Kosuke Nagasaka, DMPK Business Unit

Presentation Summary
Although drug metabolism research has mainly focused on the human liver and small intestine, the gut microbiota is currently expected to change pharmacological effects and affect interindividual variability. The methodology of in vitro drug metabolism by the microbiota remains to be standardized, though many studies have evaluated specific bacterial strains using specialized equipment.
In this study, we present a simple and practical standardized method using human fecal samples to evaluate drug metabolism mediated by the gut microbiota.

Axcelead DDP’s Soulution
We offer flexible support not only for conventional biological samples but also for studies involving uncommon cell types and enzyme sources.
Whether you are working within established frameworks or exploring novel evaluation approaches, we invite you to consult with us for expert guidance and support.