Publications Archives - Page 3 of 3 - Axcelead

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CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs

Stem Cell Research & Therapy

Michael Jaramillo2023-12-01T16:34:32+00:0001.05.2023|

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

Pharmaceutical Research

Michael Jaramillo2023-12-05T16:13:50+00:0004.11.2022|

Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC

Scientific Reports

Michael Jaramillo2023-12-05T16:12:33+00:0003.18.2022|

Reliable identification of cardiac cunduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening enviroment

Journal of Pharmacological and Toxicological Methods

Michael Jaramillo2023-12-01T16:37:40+00:0009.06.2021|

Identification of novel inhibitors of Keap1/Nrf2 by a promising method combining protein–protein interaction‑oriented library and machine learning

Scientific reports

Michael Jaramillo2023-12-05T16:14:26+00:0004.01.2021|

Cryo-EM structure of K+-bound hERG channel complexed with the blocker astemizole

Structure

Michael Jaramillo2023-12-01T16:39:28+00:0001.14.2021|

Comprehensive Cardiac Safety Assessment using hiPS-cardiomyocytes (Consortium for Safety Assessment using Human iPS Cells: CSAHi)

Current Pharmaceutical Biotechnology

Michael Jaramillo2023-12-01T16:40:50+00:0011.09.2020|

Bidirectional, non-necrotizing glomerular crescents are the critical pathology in X-linked Alport syndrome mouse model harboring nonsense mutation of human COL4A5

Scientific Reports

Michael Jaramillo2023-12-01T16:40:08+00:0011.03.2020|

Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment

Journal of Pharmacological and Toxicological Methods

Michael Jaramillo2023-12-01T16:41:42+00:0006.18.2020|

Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis

PLOS ONE

Michael Jaramillo2023-12-01T16:42:24+00:0001.28.2020|