A poster co-authored by Dr. Miura of the Translational Research Business Unit will be presented at the 20th Metabolome Symposium

2026.10.05

A poster co-authored by Dr. Miura of the Translational Research Business Unit will be presented at the 20th Metabolome Symposium in  Yamagata, Japan.
If you plan to attend the conference, we encourage you to join the session and hear the presentation.

Conference Name: the 20th Metabolome Symposium

Date & Time:October 8, 2026 (10:40-11:30 JST)

Location: Lecture Hall, Tsuruoka Metabolome Campus (Tsuruoka City Advanced Research and Industry Support Center)

Title: Investigation of storage conditions and quality control markers for metabolites and lipids in human feces

No: 1P-04

Presentation Summary
Evaluating metabolites and lipids in fecal samples is crucial for gut microbiome and disease-related research. However, the effect of storage conditions on the stability of metabolites and lipids in feces remains insufficiently understood, posing a challenge for establishing standardized storage protocols. In this study, we systematically evaluated the stability of metabolites and lipids by analyzing time-dependent changes under room temperature, 4°C, and −20°C. The results revealed that while some metabolites and lipids fluctuate within 2 to 6 hours at room temperature or 4℃, most metabolites and lipids remained stable for up to two weeks at −20°C. Furthermore, we have successfully identified each of the ratios of methionine to S-methyl-5-thioadenosine, xanthine to inosine, and N-linoleoyl leucine to 1,2-dilinoleoyl-sn-glycerol as a potential quality control marker for assessing fecal samples integrity. Based on these findings, this study provides practical guidelines for handling specimens to discover reliable disease biomarkers and advance gut microbiome research.
In this study, Axcelead contributed to metabolite measurements and statistical analyses, supporting the generation of these findings.

Axcelead’s Soulution
Accurately evaluation of metabolite and lipid changes over time, as well as storage condition-dependent effects, requires highly sophisticated analytical and data interpretation technologies. Axcelead’s metabolomics platform allows high-precision measurement and interpretation of a broad spectrum of metabolites. We accommodate diverse sample types, including cells and clinical specimens, and leverage our advanced expertise in sample preparation and quantitative analysis to comprehensively evaluate a wide range of biomolecules, including peptides, lipids, and metabolites.
Furthermore, we possess cutting-edge omics analysis technologies—such as genomics, transcriptomics (including bulk, single-cell, and spatial analysis), and proteomics (including phosphorylation analysis)—as well as　advanced bioinformatics analysis technologies, providing seamless, end-to-end support from data acquisition to biomarker discovery and pharmacological evaluation. Please feel free to contact us to discuss your analytical needs.

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